Rebound tonometry in conscious, conditioned mice avoids the acute and profound effects of anesthesia on intraocular pressure

TV Johnson, S Fan, CB Toris - Journal of ocular pharmacology and …, 2008 - liebertpub.com
Aims: The aims of this study were to evaluate the accuracy, repeatability, and safety of
multiple intraocular pressure (IOP) measurements by a commercially available rebound
tonometer in conscious, conditioned mice, and to characterize the acute and profound
effects of anesthesia on IOP in mice. Methods: To test the accuracy of the tonometer, IOPs of
CD-1 mice under ketamine/xylazine anesthesia were experimentally set and monitored with
a water manometer/transducer system following transcorneal cannulation while …
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